Comprehensive storage conditions for all FDA-approved and major investigational peptides.

Storage Temperature Classification

Category	Temperature	Examples
Frozen	−20°C to −80°C	Long-term API storage
Refrigerated	2–8°C	Most reconstituted peptides
Room temperature	20–25°C	Some stable formulations
Controlled room	15–30°C	USP definition

Light Protection

Protection Level	Requirement
Light-sensitive	Store in original carton, protect from light
Light-stable	No special light protection required

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GLP-1 Receptor Agonists

Semaglutide (Ozempic)

Parameter	Unopened	In-Use
Temperature	2–8°C	Up to 30°C
Light	Original carton	Protect from light
Shelf life (unopened)	24 months	N/A
Shelf life (in-use)	N/A	56 days (8 weeks)
Do not freeze	Yes	Yes
Do not refrigerate (in-use)	N/A	May store ≤30°C
Pen disposal	After 56 days or expiry	Discard

Semaglutide (Rybelsus — Oral)

Parameter	Specification
Temperature	20–25°C (room temp)
Light	Original carton
Shelf life	36 months
Do not freeze	Yes
Do not refrigerate	Yes
Moisture	Store dry

Tirzepatide (Mounjaro/Zepbound)

Parameter	Unopened	In-Use
Temperature	2–8°C	Room temp ≤30°C
Light	Original carton	Protect from light
Shelf life (unopened)	24 months	N/A
Shelf life (in-use)	N/A	21 days (3 weeks)
Do not freeze	Yes	Yes

Liraglutide (Victoza/Saxenda)

Parameter	Unopened	In-Use
Temperature	2–8°C	Room temp ≤30°C
Light	Original carton	Protect from light
Shelf life (unopened)	30 months	N/A
Shelf life (in-use)	N/A	30 days
Do not freeze	Yes	Yes

Exenatide (Byetta)

Parameter	Unopened	In-Use
Temperature	2–8°C	Room temp ≤25°C
Light	Protect from light	Protect from light
Shelf life (unopened)	24 months	N/A
Shelf life (in-use)	N/A	30 days
Do not freeze	Yes	Yes

Exenatide ER (Bydureon)

Parameter	Unopened	In-Use
Temperature	2–8°C	Room temp ≤25°C
Light	Original carton	Protect from light
Shelf life (unopened)	24 months	N/A
Do not freeze	Yes	Yes
Reconstitution	Use within 24 hours	Administer immediately

Dulaglutide (Trulicity)

Parameter	Unopened	In-Use
Temperature	2–8°C	Room temp ≤30°C
Light	Original carton	Protect from light
Shelf life (unopened)	24 months	N/A
Shelf life (in-use)	N/A	14 days
Do not freeze	Yes	Yes

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Amylin Analogues

Pramlintide (Symlin)

Parameter	Unopened	In-Use
Temperature	2–8°C	Room temp ≤30°C
Light	Protect from light	Protect from light
Shelf life (unopened)	24 months	N/A
Shelf life (in-use)	N/A	28 days
Do not freeze	Yes	Yes

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Insulin Analogues

Rapid-Acting Insulins

Insulin	Unopened	In-Use	Shelf Life (In-Use)
Lispro (Humalog)	2–8°C	Room temp ≤30°C	28 days
Aspart (NovoRapid)	2–8°C	Room temp ≤30°C	28 days
Glulisine (Apidra)	2–8°C	Room temp ≤30°C	28 days
Faster aspart (Fiasp)	2–8°C	Room temp ≤30°C	28 days
Technosphere (Afrezza)	2–8°C	Room temp ≤25°C	10 days (open inhaler)

Long-Acting Insulins

Insulin	Unopened	In-Use	Shelf Life (In-Use)
Glargine U-100 (Lantus)	2–8°C	Room temp ≤25°C	28 days
Glargine U-300 (Toujeo)	2–8°C	Room temp ≤30°C	42 days
Detemir (Levemir)	2–8°C	Room temp ≤30°C	42 days
Degludec (Tresiba)	2–8°C	Room temp ≤30°C	56 days
Icodec (Awiqli)	2–8°C	Room temp ≤30°C	56 days

Concentrated Insulins

Insulin	Unopened	In-Use	Shelf Life (In-Use)
Humulin R U-500	2–8°C	Room temp ≤25°C	40 days
Concentrated Lispro	2–8°C	Room temp ≤30°C	28 days

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Growth Hormone Secretagogues

Tesamorelin (Egrifta)

Parameter	Specification
Unopened	2–8°C
In-use	2–8°C (after reconstitution)
Shelf life (unopened)	24 months
Shelf life (reconstituted)	24 hours
Do not freeze	Yes
Light	Original carton

CJC-1295 DAC (Research Chemical)

Parameter	Specification
Lyophilized	−20°C (long-term) or 2–8°C
Reconstituted	2–8°C
Shelf life (lyophilized)	12–24 months
Shelf life (reconstituted)	30 days
Do not freeze (reconstituted)	Yes

Ipamorelin (Research Chemical)

Parameter	Specification
Lyophilized	−20°C (long-term) or 2–8°C
Reconstituted	2–8°C
Shelf life (lyophilized)	12–24 months
Shelf life (reconstituted)	30 days

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Melanocortin Analogues

Afamelanotide (Scenesse)

Parameter	Specification
Temperature	2–8°C
Light	Original carton
Shelf life	36 months
Do not freeze	Yes
Implant storage	Refrigerated until administration

Bremelanotide (Vyleesi)

Parameter	Unopened	In-Use
Temperature	2–8°C	Room temp ≤25°C
Light	Original carton	Protect from light
Shelf life (unopened)	24 months	N/A
Shelf life (in-use)	N/A	30 days
Do not freeze	Yes	Yes

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Somatostatin Analogues

Octreotide (Sandostatin)

Parameter	SC Vials	LAR Vials
Temperature	2–8°C	2–8°C
Light	Protect from light	Protect from light
Shelf life	24 months	24 months
Reconstituted	Use within 24 h	Use within 24 h
Do not freeze	Yes	Yes

Lanreotide (Somatuline)

Parameter	Specification
Temperature	2–8°C
Light	Original carton
Shelf life	36 months
Do not freeze	Yes
Administration	Room temp 30 min before injection

Pasireotide (Signifor)

Parameter	SC	LAR
Temperature	2–8°C	2–8°C
Light	Protect from light	Protect from light
Shelf life	24 months	24 months
Reconstituted	Use within 24 h	Use within 24 h
Do not freeze	Yes	Yes

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Repair Peptides (Research Chemicals)

BPC-157

Parameter	Specification
Lyophilized	−20°C (long-term) or 2–8°C
Reconstituted	2–8°C
Shelf life (lyophilized)	12–24 months
Shelf life (reconstituted)	30 days
Solvent	Bacteriostatic water or saline
Do not freeze (reconstituted)	Yes

Thymosin Beta-4 / TB-500

Parameter	Specification
Lyophilized	−20°C (long-term) or 2–8°C
Reconstituted	2–8°C
Shelf life (lyophilized)	12–24 months
Shelf life (reconstituted)	30 days
Solvent	Bacteriostatic water or saline
Do not freeze (reconstituted)	Yes

GHK-Cu

Parameter	Specification
Powder	2–8°C or room temp
Reconstituted	2–8°C
Shelf life (powder)	24–36 months
Shelf life (reconstituted)	30 days
Solvent	Bacteriostatic water or saline

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Reconstitution Solvents

Solvent	Use	Storage	Shelf Life
Bacteriostatic water (0.9% BA)	Most peptides	Room temp	28 days after opening
Sterile water for injection	Sensitive peptides	Room temp	24 hours after opening
Normal saline (0.9% NaCl)	IM/SC injection	Room temp	24 hours
0.9% BA in NS	Peptides requiring BA	Room temp	28 days

General Storage Rules

1. Always check expiry dates before use
2. Reconstituted peptides are typically stable for 30 days at 2–8°C
3. Do not freeze reconstituted peptides (protein denaturation risk)
4. Protect from light unless specified as light-stable
5. Do not use if solution is discolored, cloudy, or contains particles
6. In-use storage differs from unopened storage — follow label
7. Travel: Use insulated cooler with ice packs for <8 hours
8. Power outage: Keep refrigerated items cold with ice; if >24 hours without cold chain, discard reconstituted peptides
9. Multi-dose vials contain preservative; single-dose vials do not
10. Lyophilized peptides are more stable than reconstituted — store lyophilized when possible

References

• Peptide Storage Conditions
• Peptide Reconstitution Guide
• Peptide Clinical Dosing
• Peptide Safety Data
• Peptide Drug Interactions Database